Description

(3R,5S)-5-(3-Furyl)-3',4,4',5,5',6',7',8'-Octahydro-2'α,5'-Dimethyl-2-Oxospiro[Furan-3(2H),1'(2'H)-Naphthalene]-5'α-Carboxylic Acid Methyl Ester is a high-purity, complex spirocyclic compound featuring a fused furan-naphthalene core structure. This compound is of significant value as a sophisticated chemical intermediate or pharmacological research tool due to its unique three-dimensional architecture. It is primarily utilized by research and development teams in the pharmaceutical and fine chemical sectors for advanced synthetic programs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the research and development of novel active pharmaceutical ingredients (APIs), particularly for complex target molecules.
• Medicinal Chemistry Research: Used as a core scaffold or precursor in structure-activity relationship (SAR) studies and hit-to-lead optimization for new drug candidates.
• Asymmetric Synthesis: Employed in advanced organic synthesis as a chiral template or starting material for constructing stereochemically complex molecules.
• Fine Chemical Production: Acts as a specialized intermediate in the multi-step synthesis of high-value agrochemicals, flavors, or fragrances.
• Academic & Institutional Research: Utilized in university and institutional labs for methodological development in synthetic organic chemistry and catalysis studies.

Basic Information

Product Name	(3R,5S)-5-(3-Furyl)-3',4,4',5,5',6',7',8'-Octahydro-2'α,5'-Dimethyl-2-Oxospiro[Furan-3(2H),1'(2'H)-Naphthalene]-5'α-Carboxylic Acid Methyl Ester
CAS No.	78791-49-8
Molecular Formula	C22H26O5
Molecular Weight	370.44 g/mol
Synonyms	Methyl (3R,5S)-5-(3-furyl)-3',4,4',5,5',6',7',8'-octahydro-2'α,5'-dimethyl-2-oxospiro[furan-3(2H),1'(2'H)-naphthalene]-5'α-carboxylate; Spiro[furan-3(2H),1'(2'H)-naphthalene] Carboxylic Acid Derivative; (3R,5S)-Spirocyclic Furan-Naphthalene Ester; CAS 78791-49-8; 5-(3-Furyl)-octahydro-spiro[furan-3,1'-naphthalene] Methyl Ester; (3R-cis)-5-(3-Furanyl)-3',4,4',5,5',6',7',8'-octahydro-2'α,5'-dimethyl-2-oxospiro[furan-3(2H),1'(2'H)-naphthalene]-5'α-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our (3R,5S)-5-(3-Furyl)-3',4,4',5,5',6',7',8'-Octahydro-2'α,5'-Dimethyl-2-Oxospiro[Furan-3(2H),1'(2'H)-Naphthalene]-5'α-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.