Description

2-Azidophenyl Disulfide is a specialized organic compound featuring both a disulfide linkage and an azide functional group, making it a valuable bifunctional reagent. This unique structure allows it to serve as a versatile building block and cross-linking agent in advanced chemical synthesis. It is particularly relevant for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require precise molecular assembly and functionalization.

Application

• Click Chemistry Reagent: The azide group enables participation in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer synthesis.
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly those targeting disulfide-rich proteins or requiring specific molecular linkages.
• Polymer Cross-Linking Agent: Facilitates the formation of disulfide bonds within polymer networks, creating materials with redox-responsive or self-healing properties.
• Surface Functionalization: Employed to modify material surfaces (e.g., gold, silica) by forming stable monolayers via the disulfide or azide group for sensor or diagnostic applications.
• Peptide and Protein Chemistry: Acts as a reversible cross-linker or a protecting group for thiol functionalities in peptide synthesis and protein engineering.
• Agrochemical Synthesis: Serves as a key intermediate in the creation of novel active ingredients with specific modes of action.
• Ligand Synthesis for Catalysis: Used to construct complex ligand frameworks for transition metal catalysts.
• Research & Development: A critical tool in academic and industrial R&D labs for exploring new synthetic methodologies and material properties.

Basic Information

Product Name	2-Azidophenyl Disulfide
CAS No.	78715-74-9
Molecular Formula	C12H8N6S2
Molecular Weight	300.36 g/mol
Synonyms	Bis(2-azidophenyl) disulfide; 2,2'-Diazidodiphenyl disulfide; (Azidosulfanyl)(2-azidophenyl)sulfane; Disulfide, bis(2-azidophenyl); 2-Azidobenzenethiol, disulfide
EINECS	Contact for details

Quality Control

Our 2-Azidophenyl Disulfide is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR) for structural confirmation, to ensure consistency and reliability. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to the presence of the azide functional group, standard safety precautions for azide compounds should be observed. Keep away from heat, sparks, open flames, and strong reducing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content (KF)	< 0.5%
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.