Description

Methyl 5-Bromo-2-Chloropyridine-3-Carboxylate is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the construction of complex molecules with precise substitution patterns. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of organic electronic materials and functional polymers due to its modifiable ester and halogen groups.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 5-Bromo-2-Chloropyridine-3-Carboxylate
CAS No.	78686-79-0
Molecular Formula	C7H5BrClNO2
Molecular Weight	250.48 g/mol
Synonyms	5-Bromo-2-chloropyridine-3-carboxylic acid methyl ester; Methyl 5-bromo-2-chloro-3-pyridinecarboxylate; 3-Pyridinecarboxylic acid, 5-bromo-2-chloro-, methyl ester; 2-Chloro-5-bromonicotinic acid methyl ester; 5-Bromo-2-chloro-3-(methoxycarbonyl)pyridine; Methyl 2-chloro-5-bromonicotinate
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-2-Chloropyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.