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4-(Dimethylamino)-1-(Triphenylmethyl)Pyridinium Chloride CAS NO 78646-25-0


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CAS No.:78646-25-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-(Dimethylamino)-1-(Triphenylmethyl)Pyridinium Chloride is a specialized quaternary ammonium salt with a unique trityl-protected pyridinium structure. This compound is valued for its role as a key intermediate and protecting group reagent in advanced organic synthesis, particularly in the development of pharmaceuticals and fine chemicals. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for complex molecule assembly.

Application

  • Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing protected amine functionalities.
  • Nucleoside & Nucleotide Chemistry: Used as a protecting group reagent for hydroxyl functions during the synthesis of modified nucleosides and oligonucleotides.
  • Peptide Synthesis: Employed in the protection of amino acid side chains, facilitating the synthesis of complex peptides.
  • Catalyst & Ligand Precursor: Acts as a precursor for generating specialized catalysts or ligands used in asymmetric synthesis and cross-coupling reactions.
  • Fine Chemical Synthesis: Utilized in the multi-step synthesis of dyes, pigments, and other high-value specialty chemicals.
  • Academic & Industrial R&D: A valuable reagent for method development and exploratory research in synthetic organic chemistry laboratories.

Basic Information

Product Name 4-(Dimethylamino)-1-(Triphenylmethyl)Pyridinium Chloride
CAS No. 78646-25-0
Molecular Formula C26H25ClN2
Molecular Weight 400.94 g/mol
Synonyms 1-Trityl-4-(dimethylamino)pyridinium Chloride; 4-Dimethylamino-1-tritylpyridinium Chloride; N,N-Dimethyl-4-(triphenylmethyl)aminopyridinium Chloride; DMT-Pyridinium Chloride; Trityl-DMAP Chloride; 4-(Dimethylamino)pyridinium Trityl Chloride; 4-DMAP-Trityl Chloride
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Quality Control

Our 4-(Dimethylamino)-1-(Triphenylmethyl)Pyridinium Chloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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