Description

2-Chloro-3-Iodopyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both chlorine and iodine substituents, makes it a highly valuable intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the pyridine core provides essential bioactivity.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for transition metal catalysts used in cross-coupling reactions (e.g., Suzuki, Negishi).
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Useful as a tagging or labeling reagent for probing biological systems and protein interactions due to its reactive halogen sites.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring specific halogenated heterocycles.

Basic Information

Product Name	2-Chloro-3-Iodopyridine
CAS No.	78607-36-0
Molecular Formula	C5H3ClIN
Molecular Weight	239.44 g/mol
Synonyms	3-Iodo-2-chloropyridine; 2-Chloro-3-iodopyridine; Pyridine, 2-chloro-3-iodo-; 2-Chloro-3-iodo-pyridine; 78607-36-0; 3-Iodo-2-chloro-pyridine; 2-Chloro-3-iodo pyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-Iodopyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support compliance with cGMP and ICH guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.