Description

5(S),6(R),7-Trihydroxyheptanoic Acid, Methyl Ester is a high-purity, chiral hydroxy fatty acid ester with significant synthetic utility. This compound serves as a versatile and valuable chiral building block in advanced organic synthesis, particularly for the construction of complex natural products and bioactive molecules. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemistry for developing new active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandins, leukotrienes, and other bioactive lipid mediators.
• Asymmetric Synthesis: Used as a starting material or precursor in stereoselective reactions to introduce multiple chiral centers.
• Natural Product Synthesis: Critical building block for the total synthesis of complex natural products containing polyhydroxylated chains.
• Agrochemical Research: Intermediate in the development of novel, stereospecific pesticides and plant growth regulators.
• Biochemical Research: Probe or substrate for studying enzyme mechanisms related to fatty acid oxidation and modification.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	5(S),6(R),7-Trihydroxyheptanoic Acid, Methyl Ester
CAS No.	78606-80-1
Molecular Formula	C8H16O5
Molecular Weight	192.21 g/mol
Synonyms	Methyl (5S,6R,7R)-5,6,7-Trihydroxyheptanoate; Methyl 5,6,7-Trihydroxyheptanoate; 5(S),6(R),7(R)-Trihydroxyheptanoic Acid Methyl Ester; Heptanoic acid, 5,6,7-trihydroxy-, methyl ester, (5S,6R,7R)-; PGJ2 Methyl Ester Synthetic Intermediate; Chiral Trihydroxy Heptanoate Ester
EINECS	Contact for details

Quality Control

Our 5(S),6(R),7-Trihydroxyheptanoic Acid, Methyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high stereochemical purity. We employ advanced analytical techniques, including chiral HPLC and NMR spectroscopy, to verify identity, purity, and enantiomeric excess. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.