Description

Ethyl α-Iodophenylacetate is a high-purity, versatile organic intermediate characterized by its reactive iodine and ester functional groups. This compound is crucial for facilitating complex molecular transformations in advanced synthetic chemistry, offering a reliable building block for constructing intricate pharmaceutical and agrochemical scaffolds. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in process development and active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other arylacetic acid derivatives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and plant growth regulators, leveraging its reactive site for carbon-carbon bond formation.
• Chemical Research & Development: Serves as a versatile reagent in organic synthesis for cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions in laboratory-scale and pilot-plant settings.
• Ligand and Catalyst Preparation: Employed in the development of novel organometallic catalysts and chiral ligands for asymmetric synthesis.
• Fine Chemical Manufacturing: Acts as a building block for producing dyes, pigments, and other performance chemicals requiring specific aryl-acetate structures.

Basic Information

Item	Detail
Product Name	Ethyl α-Iodophenylacetate
CAS No.	78489-65-3
Molecular Formula	C10H11IO2
Molecular Weight	290.10 g/mol
Synonyms	Ethyl 2-Iodo-2-phenylacetate; (±)-Ethyl 2-Iodo-2-phenylacetate; Ethyl (2-Iodo-2-phenyl)acetate; α-Iodophenylacetic Acid Ethyl Ester; 2-Iodo-2-phenylacetic Acid Ethyl Ester; Ethyl α-Iodobenzeneacetate; NSC 334153; Ethyl (iodophenyl)acetate
EINECS	Contact for details

Quality Control

Our Ethyl α-Iodophenylacetate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.