Description

Methyl 5-Oxobicyclo[2.2.2]Octane-2-Carboxylate is a specialized bicyclic ester compound that serves as a valuable synthetic intermediate in advanced organic chemistry. Its unique, rigid bicyclo[2.2.2]octane framework makes it a critical building block for constructing complex molecular architectures with precise stereochemistry. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical sectors, where it is used to synthesize novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those requiring rigid, three-dimensional scaffolds for targeted biological activity.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the creation of advanced polymers and specialty chemicals where the bicyclic structure imparts specific thermal or mechanical properties.
• Organic Synthesis & Catalysis: Serves as a model substrate or ligand precursor in methodological development and asymmetric catalysis research.
• Fragrance & Flavor Chemistry: Intermediate for synthesizing unique odorants and flavor compounds that leverage its constrained molecular geometry.
• Academic & Industrial R&D: Fundamental reagent for exploring new chemical reactions and synthesizing natural product analogs in laboratory settings.

Basic Information

Product Name	Methyl 5-Oxobicyclo[2.2.2]Octane-2-Carboxylate
CAS No.	78478-61-2
Molecular Formula	C10H14O3
Molecular Weight	182.22 g/mol
Synonyms	5-Oxobicyclo[2.2.2]octane-2-carboxylic acid methyl ester; Methyl 5-oxobicyclo[2.2.2]octane-2-carboxylate; 2-Carbomethoxy-5-oxobicyclo[2.2.2]octane; Methyl 2-bicyclo[2.2.2]octanone-5-carboxylate; Bicyclo[2.2.2]octane-2-carboxylic acid, 5-oxo-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Oxobicyclo[2.2.2]Octane-2-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements of pharmaceutical and advanced chemical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.