Description

Methyl 4-Bromo-2-Bromomethyl-Benzoate is a high-purity, multi-functional brominated aromatic ester that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring two distinct bromine substituents, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce bromine atoms or benzyl bromide functionalities with precision.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring brominated aromatic or benzyl-protected motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromomethyl group acts as a reactive handle for further derivatization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphine ligands or metal-organic frameworks (MOFs) with tailored properties.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or monomers for conductive polymers.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) due to its aryl bromide functionality.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags where the benzyl bromide group allows for selective bioconjugation.

Basic Information

Product Name	Methyl 4-Bromo-2-Bromomethyl-Benzoate
CAS No.	78471-43-9
Molecular Formula	C9H8Br2O2
Molecular Weight	307.97 g/mol
Synonyms	Methyl 4-bromo-2-(bromomethyl)benzoate; 2-Bromomethyl-4-bromobenzoic Acid Methyl Ester; Benzoic acid, 4-bromo-2-(bromomethyl)-, methyl ester; Methyl 2-(bromomethyl)-4-bromobenzoate; 4-Bromo-2-bromomethylbenzoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-2-Bromomethyl-Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for use in cGMP-compliant pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.