Description

(2R,3S)-(+)-3-(Benzyloxymethyl)Oxirane-2-Methanol 4-Nitrobenzoic Acid Ester is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its defined stereochemistry and protected functional groups make it a critical reagent for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of potential drug candidates, particularly for antiviral, anticancer, or neurological targets.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides, where specific stereochemistry can influence biological activity and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands used in asymmetric catalysis, such as for epoxidation or hydroxylation reactions.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, flavors, fragrances, and other high-value specialty chemicals.
• Academic & Process Chemistry: A valuable tool in methodological research for developing new synthetic routes and studying stereoselective transformations.

Basic Information

Product Name	(2R,3S)-(+)-3-(Benzyloxymethyl)Oxirane-2-Methanol 4-Nitrobenzoic Acid Ester
CAS No.	78469-86-0
Molecular Formula	C18H17NO6
Molecular Weight	343.33 g/mol
Synonyms	(2R,3S)-3-(Benzyloxymethyl)oxirane-2-methanol 4-nitrobenzoate; (+)-3-(Benzyloxymethyl)glycidyl 4-Nitrobenzoate; (2R,3S)-Glycidyl Benzyl Ether 4-Nitrobenzoate; 4-Nitrobenzoic Acid (2R,3S)-3-(Benzyloxymethyl)oxiranyl Methyl Ester; (2R,3S)-Epoxy Alcohol 4-Nitrobenzoate Derivative; Bn-Protected Glycidol 4-Nitrobenzoate; (2R,3S)-1-(Benzyloxymethyl)-2,3-epoxypropyl 4-nitrobenzoate
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity, which is critical for downstream synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, and NMR to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.