Description

D-Isovaline, Methyl Ester (9Ci) is a chiral, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial chiral building block and synthetic intermediate for the development of novel bioactive molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring high stereochemical purity.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in neurological and metabolic disorder research.
• Agrochemical Synthesis: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators requiring specific stereochemistry for enhanced efficacy.
• Peptidomimetics & Bioactive Molecule Design: Serves as a constrained amino acid analog in the design of novel peptides and enzyme inhibitors.
• Asymmetric Catalysis & Ligand Development: Employed as a precursor for chiral ligands and catalysts used in stereoselective synthesis.
• Chemical Biology Research: Utilized as a probe or building block in studying biological pathways and protein interactions.
• Reference Standard: Acts as a high-purity analytical standard for method development and quality control in chiral analysis.

Basic Information

Product Name	D-Isovaline, Methyl Ester (9Ci)
CAS No.	78410-93-2
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	Methyl (R)-2-amino-2-methylbutanoate; (R)-2-Amino-2-methylbutyric acid methyl ester; D-2-Aminoisovaleric acid methyl ester; Methyl D-2-aminoisovalerate; (R)-2-Aminoisovaleric Acid Methyl Ester; D-α-Aminoisovaleric Acid Methyl Ester; (R)-2-Methyl-2-aminobutanoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our D-Isovaline, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its properties, the material should be handled in a manner that minimizes exposure to moisture and excessive heat. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.