Description

n-Palmitoylmuramyl-Alanyl-Isoglutamine is a synthetic lipopeptide derivative of muramyl dipeptide (MDP), a key immunostimulatory component of bacterial cell walls. This compound is valued for its potent adjuvant activity, enhancing and modulating immune responses in various formulations. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of novel vaccines and immunotherapies. The product is supplied under stringent quality control to ensure consistency for critical research and development applications.

Application

• Vaccine Adjuvant Development: As a potent immunomodulator to enhance the efficacy and longevity of immune responses in next-generation vaccine formulations.
• Immunology Research: Used as a standard or experimental tool to study innate immune system activation, particularly through NOD2 receptor pathways.
• Pharmaceutical Intermediates: Serves as a key synthetic building block for more complex immunostimulatory compounds and conjugates.
• Bioconjugation Studies: Employed in the development of carrier systems and targeted drug delivery platforms due to its lipophilic palmitoyl tail.
• Animal Health Products: Investigated for use in veterinary vaccines to improve protective immunity.

Basic Information

Product Name	n-Palmitoylmuramyl-Alanyl-Isoglutamine
CAS No.	78408-99-8
Molecular Formula	C46H83N5O13
Molecular Weight	914.18 g/mol
Synonyms	Pam2C-MDP; N-Palmitoyl-MDP; L18-MDP; MTP-PE Lipopeptide; Muramyl Dipeptide Palmitoyl Derivative; N-Acetylmuramyl-L-alanyl-D-isoglutamine with N-Palmitoyl; N-Palmitoyl-N-acetylmuramyl-L-alanyl-D-isoglutamine; Immunostimulant Peptide 18
EINECS	Contact for details

Quality Control

Our n-Palmitoylmuramyl-Alanyl-Isoglutamine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency suitable for research and development. Quality is verified through a comprehensive suite of analytical techniques including HPLC, MS, and NMR. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere or with desiccant to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.