Description

Anhydroepipicropodophyllol is a specialized organic compound belonging to the lignan family, structurally related to podophyllotoxin. This compound serves as a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis and study of novel chemotherapeutic agents and bioactive molecules. Its defined structure and high purity make it essential for analytical method development and biochemical pathway investigation.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for developing potential anticancer and antiviral agents.
• Reference Standard: Used in analytical laboratories for quality control, method validation, and identification via techniques like HPLC and LC-MS.
• Biochemical Research: Employed in studies investigating the mechanism of action of tubulin inhibitors and other cytostatic compounds.
• Organic Synthesis: Serves as a precursor for the semi-synthesis of more complex lignan derivatives with targeted biological activity.
• Academic Research: Utilized in university and institutional labs for pharmacological screening and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Anhydroepipicropodophyllol
CAS No.	78391-86-3
Molecular Formula	C22H20O7
Molecular Weight	396.39 g/mol
Synonyms	Anhydroepipicropodophyllol; 4'-Demethylepipodophyllotoxin; 4'-Demethyl-4-epipodophyllotoxin; 4'-Demethylepipodophyllotoxine; NSC 334753; 4-Epi-4'-demethylpodophyllotoxin; (5R,5aR,8aR,9S)-9-Hydroxy-5-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
EINECS	Contact for details

Quality Control

Our Anhydroepipicropodophyllol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production standards. Specifications can be aligned with pharmacopeial requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.