Description

(S)-(-)-3-Hydroxy-2-Pyrrolidone is a high-purity chiral building block and intermediate of significant synthetic utility. This compound matters for its role in the stereoselective synthesis of pharmaceuticals and fine chemicals, where its defined stereochemistry is critical for biological activity. It is needed by research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on creating enantiomerically pure compounds, such as nootropic agents and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly nootropics and cognitive enhancers.
• Asymmetric Synthesis: Used as a building block for constructing complex molecules with defined stereocenters in medicinal chemistry research.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high optical purity.
• Biochemical Research: Serves as a precursor or reference standard in studies involving pyrrolidone-based bioactive compounds.
• Agrochemical Development: Potential intermediate for creating chiral active ingredients with specific modes of action.

Basic Information

Product Name	(S)-(-)-3-Hydroxy-2-Pyrrolidone
CAS No.	78340-48-4
Molecular Formula	C4H7NO2
Molecular Weight	101.10 g/mol
Synonyms	(S)-3-Hydroxy-2-pyrrolidinone; (S)-3-Hydroxypyrrolidin-2-one; (-)-3-Hydroxy-2-pyrrolidone; (S)-(-)-3-Hydroxy-2-pyrrolidinone; L-3-Hydroxy-2-pyrrolidinone; (S)-3-Hydroxy-2-azacyclopentanone; (S)-3-Hydroxybutyrolactam
EINECS	Contact for details

Quality Control

Our (S)-(-)-3-Hydroxy-2-Pyrrolidone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing specific results for chiral purity, chemical purity, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.