Description

Podophyllol is a naturally occurring lignan derivative, recognized for its complex molecular structure and significant biological activity. This compound serves as a crucial intermediate and reference standard in the research and development of novel pharmaceutical agents. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for applications in medicinal chemistry, phytochemical analysis, and as a precursor for further chemical synthesis.

Application

• Pharmaceutical Intermediate: A key starting material or precursor in the synthesis of more complex therapeutic agents, particularly those targeting specific cellular pathways.
• Reference Standard: Used in analytical laboratories for the qualitative and quantitative analysis (e.g., via HPLC, LC-MS) of plant extracts and related products.
• Medicinal Chemistry Research: Employed in drug discovery programs to study structure-activity relationships (SAR) and develop new bioactive compounds.
• Phytochemical Studies: Serves as a marker compound in the isolation, identification, and standardization of botanical ingredients.
• Biochemical Research: Investigated for its potential biological activities and mechanisms of action in various in vitro and in vivo studies.

Basic Information

Product Name	Podophyllol
CAS No.	78339-51-2
Molecular Formula	C22H22O8
Molecular Weight	414.41 g/mol
Synonyms	Podophyllol; 5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one; (-)-Podophyllol; NSC 368390; 4-[(1R,2S,3R)-3-Hydroxy-2-(hydroxymethyl)-1,2,3,4-tetrahydro-1-naphthalenyl]-2,6-dimethoxyphenol (related isomer).
EINECS	Contact for details

Quality Control

Our Podophyllol is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, purity, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.