Description

N,n-Bis(2-Chloroethyl)-1,3,2-Oxazaphosphonan-2-Amine CAS NO 78219-90-6 is a specialized organophosphorus compound featuring a unique oxazaphosphinane ring structure. This chemical is a critical intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel therapeutic agents, including potential anticancer and antiviral compounds.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its reactive phosphorous and nitrogen centers.
• Ligand and Catalyst Precursor: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for constructing complex heterocyclic frameworks in academic and industrial R&D settings.
• Material Science Research: Investigated for incorporation into polymers or functional materials requiring specific phosphorus-containing motifs.

Basic Information

Product Name	N,n-Bis(2-Chloroethyl)-1,3,2-Oxazaphosphonan-2-Amine
CAS No.	78219-90-6
Molecular Formula	C7H15Cl2N2OP
Molecular Weight	245.09 g/mol
Synonyms	2-Amino-N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinane; 2-Amino-N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphorinane; 1,3,2-Oxazaphosphinan-2-amine, N,N-bis(2-chloroethyl)-; N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine; Cyclophosphamide Impurity; Oxazaphosphorine derivative
EINECS	Contact for details

Quality Control

Every batch of N,n-Bis(2-Chloroethyl)-1,3,2-Oxazaphosphonan-2-Amine is produced and tested under strict quality management protocols to ensure consistency and purity for research applications. Our standard grade meets high-purity specifications suitable for synthetic chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC or NMR), and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.