Description

3-Bromo-5-Methoxypyridine-1-Oxide is a versatile heterocyclic building block and key intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its halogen and methoxy substituents for structure-activity relationship (SAR) studies.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive components.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or molecular probes for studying biological pathways and mechanisms.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.

Basic Information

Product Name	3-Bromo-5-Methoxypyridine-1-Oxide
CAS No.	78156-39-5
Molecular Formula	C6H6BrNO2
Molecular Weight	204.02 g/mol
Synonyms	3-Bromo-5-methoxypyridine N-oxide; 5-Methoxy-3-bromopyridine 1-oxide; 3-Bromo-5-methoxypyridine 1-oxide; Pyridine, 3-bromo-5-methoxy-, 1-oxide; 3-Bromo-5-methoxypyridine N-Oxide; 3-Br-5-MeO-Pyridine N-Oxide; 78156-39-5
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Methoxypyridine-1-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates, from early-stage R&D to cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.