Description

5-Iodo-4-Hydroxy-7,10,13,16,19-Docosapentaenoic Acid γ-Lactone is a specialized iodinated fatty acid lactone derivative, representing a high-value synthetic intermediate for advanced organic synthesis and pharmaceutical research. This compound is particularly significant for its unique molecular architecture, combining a polyunsaturated fatty acid chain with an iodine substituent and a lactone ring, which makes it a versatile building block for creating novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical developers working on lipid-based drug discovery, targeted probe synthesis, and the study of complex metabolic pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting lipid metabolism, inflammation, and neurological disorders.
• Biochemical Research: Used as a molecular probe or a labeled standard in lipidomics research to study the role of iodinated lipids in biological systems.
• Organic Synthesis Building Block: The reactive iodine and lactone functionalities make it a valuable scaffold for constructing complex natural product analogs and specialized polymers.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	5-Iodo-4-Hydroxy-7,10,13,16,19-Docosapentaenoic Acid γ-Lactone
CAS No.	78144-19-1
Molecular Formula	C22H31IO3
Molecular Weight	470.39 g/mol
Synonyms	4-Hydroxy-5-iodo-7,10,13,16,19-docosapentaenoic acid γ-lactone; 5-Iodo-4-hydroxy-DPA γ-lactone; 5-I-4-OH-DPA lactone; Iodinated docosapentaenoic acid lactone; 78144-19-1; γ-Lactone of 5-iodo-4-hydroxydocosapentaenoic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Iodo-4-Hydroxy-7,10,13,16,19-Docosapentaenoic Acid γ-Lactone is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as assay, impurity profile, and spectroscopic identification.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.