Description

5α-Dihydrolevonorgestrel is a synthetic progestin and a key pharmaceutical intermediate derived from levonorgestrel. This compound is valued for its high purity and structural specificity, making it a critical building block in advanced pharmaceutical synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development and production of steroidal drugs and hormonal therapies.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of advanced steroidal active pharmaceutical ingredients (APIs).
• Hormone Research: Used in biochemical and pharmacological research to study progestin activity and receptor binding.
• Contraceptive Development: A key component in the R&D of next-generation hormonal contraceptives and related therapeutic agents.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Process Chemistry: Utilized in scale-up and process optimization for the manufacturing of related progestogen compounds.

Basic Information

Product Name	5α-Dihydrolevonorgestrel
CAS No.	78088-19-4
Molecular Formula	C21H28O2
Molecular Weight	312.45 g/mol
Synonyms	13β-Ethyl-17β-hydroxy-18,19-dinor-17α-pregn-4-en-20-yn-3-one; 5α-Dihydro-LNG; 5α-DHL; 5α-H2-Levonorgestrel; 17α-Ethynyl-17β-hydroxy-5α-estran-3-one; 5α-Dihydro-levonorgestrel; 5α-Dihydro-norgestrel; (5α,13β,17α)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one
EINECS	Contact for details

Quality Control

Our 5α-Dihydrolevonorgestrel is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.