Description

1-(5-Bromo-2,4-Dihydroxyphenyl)-3-(2-Hydroxyphenyl)-2-Propen-1-One is a specialized chalcone derivative, a class of organic compounds known for their diverse biological activities and utility in advanced chemical synthesis. This high-purity intermediate is critical for research and development in pharmaceutical and fine chemical sectors where precise molecular structure is paramount. It is primarily sought by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), UV absorbers, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and microbial infections.
• Organic Synthesis Research: Used as a versatile precursor for constructing complex heterocyclic compounds and natural product analogs in academic and industrial laboratories.
• Material Science: Investigated for potential application in the development of organic semiconductors, photochromic materials, and non-linear optical (NLO) materials.
• Cosmetic Ingredient Research: Explored for its UV-absorbing properties as a potential component in advanced sunscreen formulations.
• Biochemical Probe: Utilized in biochemical assays to study enzyme inhibition and cellular signaling pathways due to its chalcone scaffold.
• Agrochemical Research: Acts as an intermediate in the development of new plant growth regulators or agrochemicals with specific biological activity.

Basic Information

Item	Details
Product Name	1-(5-Bromo-2,4-Dihydroxyphenyl)-3-(2-Hydroxyphenyl)-2-Propen-1-One
CAS No.	78050-57-4
Molecular Formula	C15H11BrO4
Molecular Weight	335.15 g/mol
Synonyms	5'-Bromo-2',4,2-Trihydroxychalcone; 1-(5-Bromo-2,4-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-propen-1-one; 2-Propen-1-one, 1-(5-bromo-2,4-dihydroxyphenyl)-3-(2-hydroxyphenyl)-; (E)-1-(5-Bromo-2,4-dihydroxyphenyl)-3-(2-hydroxyphenyl)prop-2-en-1-one; 5-Bromo-2',4,2-trihydroxychalcone; NSC 407303; Br-THC
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-2,4-Dihydroxyphenyl)-3-(2-Hydroxyphenyl)-2-Propen-1-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates. Specifications are designed to meet the rigorous demands of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized (store under inert atmosphere), prolonged exposure to air, light, or elevated temperatures should be avoided. For long-term storage, consider packaging under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.