Description

1-(5-Bromo-2,4-Dihydroxyphenyl)-3-(3,4-Dihydroxyphenyl)-2-Propen-1-One is a specialized synthetic chalcone derivative, a class of compounds known for their significant biological and chemical activity. This high-purity intermediate is critical for research and development in advanced organic synthesis and pharmaceutical discovery. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and metabolic disorders.
• Biochemical Research: Used as a reference standard or probe in studying enzyme inhibition, antioxidant activity, and structure-activity relationships (SAR) of polyphenolic compounds.
• Organic Synthesis: Acts as a versatile precursor for synthesizing more complex heterocyclic compounds, such as flavones and aurones, due to its reactive α,β-unsaturated ketone moiety.
• Material Science Research: Investigated for potential applications in developing organic semiconductors or UV-absorbing materials due to its conjugated aromatic system.
• Agrochemical Development: Explored as a lead structure for creating new plant growth regulators or protective agents.

Basic Information

Product Name	1-(5-Bromo-2,4-Dihydroxyphenyl)-3-(3,4-Dihydroxyphenyl)-2-Propen-1-One
CAS No.	78050-55-2
Molecular Formula	C15H11BrO5
Molecular Weight	351.15 g/mol
Synonyms	5'-Bromo-2',4,3,4'-Tetrahydroxychalcone; 3-(3,4-Dihydroxyphenyl)-1-(5-bromo-2,4-dihydroxyphenyl)prop-2-en-1-one; Butein 5'-bromo derivative; 1-(5-Bromo-2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)propenone; NSC 407303; Chalcone derivative 78050-55-2; 2-Propen-1-one, 1-(5-bromo-2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-2,4-Dihydroxyphenyl)-3-(3,4-Dihydroxyphenyl)-2-Propen-1-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider storage under an inert gas such as argon or nitrogen in a freezer (-20°C). Keep the container tightly sealed to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.