Description

1-(5-Bromo-2,4-Dihydroxyphenyl)-3-(3-Hydroxy-4-Methoxyphenyl)-2-Propen-1-One is a specialized chalcone derivative, a class of compounds known for their significant biological and chemical activity. This high-purity intermediate is critical for research and development in advanced organic synthesis, particularly for creating novel molecules with targeted properties. It serves as a key building block for scientists and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new active ingredients or functional compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, or microbial infections, leveraging the bioactive chalcone scaffold.
• Agrochemical Research: Used in developing new-generation pesticides, herbicides, or plant growth regulators, where its brominated and hydroxylated structure can be modified for specific biological activity.
• Organic Synthesis Building Block: Acts as a versatile starting material for synthesizing more complex heterocyclic compounds, such as flavones, pyrazolines, or other fused-ring systems important in medicinal chemistry.
• Material Science Research: Investigated for potential use in creating organic semiconductors, photochromic materials, or non-linear optical (NLO) materials due to its conjugated system and substituent effects.
• Biochemical Research: Employed as a standard or probe in studies investigating enzyme inhibition, antioxidant mechanisms, or structure-activity relationships (SAR) of polyphenolic compounds.
• Cosmetic Ingredient Development: Explored for potential use in skincare formulations for its UV-absorbing properties and antioxidant capacity derived from its dihydroxyphenyl structure.

Basic Information

Product Name	1-(5-Bromo-2,4-Dihydroxyphenyl)-3-(3-Hydroxy-4-Methoxyphenyl)-2-Propen-1-One
CAS No.	78050-54-1
Molecular Formula	C16H13BrO5
Molecular Weight	365.18 g/mol
Synonyms	5'-Bromo-2',4'-dihydroxy-3-hydroxy-4-methoxychalcone; (E)-1-(5-Bromo-2,4-dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)prop-2-en-1-one; 3-(3-Hydroxy-4-methoxyphenyl)-1-(5-bromo-2,4-dihydroxyphenyl)-2-propen-1-one; Brominated Chalcone Derivative; NSC 407296; Chalcone, 1-(5-bromo-2,4-dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-; 2-Propen-1-one, 1-(5-bromo-2,4-dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-, (E)-
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-2,4-Dihydroxyphenyl)-3-(3-Hydroxy-4-Methoxyphenyl)-2-Propen-1-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. Certificates of Analysis (COA) detailing all test results are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.