Description

1-(5-Bromo-2,4-Dihydroxyphenyl)-3-(4-Methoxyphenyl)-2-Propen-1-One is a specialized chalcone derivative, a class of organic compounds known for their diverse biological activities and utility as key synthetic intermediates. This compound matters for its role as a high-value building block in pharmaceutical research and fine chemical synthesis, offering a unique brominated, dihydroxylated structure for targeted molecular development. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and microbial infections.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its chalcone scaffold for bioactive molecule design.
• Organic Synthesis Building Block: The reactive α,β-unsaturated ketone (enone) and bromine substituent make it a versatile intermediate for cross-coupling reactions, cyclizations, and further functionalization.
• Material Science Research: Investigated for potential use in organic electronic materials or as a ligand in metal-organic frameworks due to its conjugated system and phenolic groups.
• Biochemical Tool Compound: Utilized in biochemical assays and as a standard in analytical research to study chalcone-related biological pathways.

Basic Information

Product Name	1-(5-Bromo-2,4-Dihydroxyphenyl)-3-(4-Methoxyphenyl)-2-Propen-1-One
CAS No.	78050-52-9
Molecular Formula	C₁₆H₁₃BrO₄
Molecular Weight	349.18 g/mol
Synonyms	5'-Bromo-2',4'-Dihydroxy-4-Methoxychalcone; (E)-1-(5-Bromo-2,4-Dihydroxyphenyl)-3-(4-Methoxyphenyl)prop-2-en-1-one; 5-Bromo-2,4-Dihydroxy-4'-Methoxychalcone; 2-Propen-1-one, 1-(5-bromo-2,4-dihydroxyphenyl)-3-(4-methoxyphenyl)-; 4-Methoxy-5'-bromochalcone derivative; BDP-MPC; Light-sensitive chalcone derivative
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-2,4-Dihydroxyphenyl)-3-(4-Methoxyphenyl)-2-Propen-1-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling should be performed under subdued lighting or in amber glass containers when possible.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.