Description

4-Amino-5-Pyridin-3-Yl-4H-[1,2,4]Triazole-3-Thiol is a heterocyclic organic compound featuring a fused triazole-thiol structure with an amino and pyridinyl substituent, serving as a versatile and high-value synthetic intermediate. Its molecular architecture makes it a critical precursor for developing advanced pharmaceuticals, agrochemicals, and specialty materials. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and material science industries seeking to create novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for antiviral, anticancer, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and plant growth regulators.
• Coordination Chemistry & Ligand: Acts as a chelating ligand for metal ions in catalysis and the creation of metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and advanced organic electronic materials.
• Biochemical Research: Serves as a scaffold for enzyme inhibitors and probes in biochemical and pharmacological studies.
• Custom Synthesis & Contract Manufacturing: A high-purity starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	4-Amino-5-Pyridin-3-Yl-4H-[1,2,4]Triazole-3-Thiol
CAS No.	78027-00-6
Molecular Formula	C7H7N5S
Molecular Weight	193.23 g/mol
Synonyms	4-Amino-3-mercapto-5-(3-pyridinyl)-1H-1,2,4-triazole; 5-(3-Pyridyl)-4-amino-1,2,4-triazole-3-thiol; 3-Pyridyl-4-amino-1,2,4-triazole-5-thiol; 4-Amino-5-(3-pyridinyl)-1H-1,2,4-triazole-3-thiol; 4-Amino-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol; 3-Mercapto-4-amino-5-(3-pyridyl)-1,2,4-triazole; 78027-00-6; 4-Amino-5-(3-pyridyl)-1,2,4-triazole-3-thiol
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Pyridin-3-Yl-4H-[1,2,4]Triazole-3-Thiol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates, including those under cGMP guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent oxidation and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.