Description

[(Cholest-4-Ene-3α,6β-Diyl)Bisoxy]Bis(Trimethylsilane) is a high-purity, organosilicon-protected steroid derivative. This compound is a critical synthetic intermediate, valued for its role in introducing silyl ether protecting groups to sensitive hydroxyl functionalities in complex organic synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel steroid-based therapeutics and advanced chemical probes.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of novel steroid drugs and hormone analogs.
• Organic Synthesis Reagent: Used as a protecting group agent for hydroxyl functions in complex molecule construction, enabling selective reactions.
• Biochemical Research: Employed in the preparation of labeled or modified steroid compounds for metabolic pathway studies and receptor binding assays.
• Material Science Precursor: Potential starting material for creating functionalized organic-inorganic hybrid materials with specific surface properties.

Basic Information

Product Name	[(Cholest-4-Ene-3α,6β-Diyl)Bisoxy]Bis(Trimethylsilane)
CAS No.	77847-00-8
Molecular Formula	C33H62O2Si2
Molecular Weight	546.99 g/mol
Synonyms	3α,6β-Bis(trimethylsilyloxy)cholest-4-ene; Cholest-4-ene-3α,6β-diol, 3,6-bis(trimethylsilyl) ether; 3α,6β-Di-O-trimethylsilylcholest-4-ene; 3,6-Bis-O-(trimethylsilyl)cholest-4-ene-3α,6β-diol; Silylated Cholest-4-ene-3α,6β-diol; TMS-protected cholestenediol
EINECS	Contact for details

Quality Control

Our production of [(Cholest-4-Ene-3α,6β-Diyl)Bisoxy]Bis(Trimethylsilane) adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.