Description

3β,6α-Bis[(Trimethylsilyl)Oxy]Cholest-4-Ene CAS NO 77828-35-4 is a high-purity, organosilicon-protected derivative of cholest-4-ene, serving as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its role in introducing silyl ether protecting groups, which are essential for the selective manipulation of steroid and complex molecule frameworks during multi-step synthesis. It is primarily required by research institutions and pharmaceutical development laboratories engaged in the synthesis of novel steroid analogs, drug metabolites, and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Organic Synthesis Reagent: Used as a protected intermediate in complex multi-step organic syntheses, particularly for introducing specific functional groups at defined positions.
• Biochemical Research: Employed in academic and industrial research to study steroid metabolism, enzyme interactions, and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in chromatographic analysis (HPLC, GC).
• Material Science Precursor: Potential use in the synthesis of advanced organic materials and liquid crystals due to its modified steroid core.

Basic Information

Product Name	3β,6α-Bis[(Trimethylsilyl)Oxy]Cholest-4-Ene
CAS No.	77828-35-4
Molecular Formula	C33H60O2Si2
Molecular Weight	544.99 g/mol
Synonyms	Cholest-4-ene-3β,6α-diyl bis(trimethylsilyl) ether; 3β,6α-Bis(trimethylsiloxy)cholest-4-ene; 3β,6α-Bis-O-(trimethylsilyl)cholest-4-ene; 3β,6α-Di(trimethylsiloxy)cholest-4-ene; 3β,6α-Bis(trimethylsilyloxy)cholest-4-ene; 3,6-Bis-O-trimethylsilylcholest-4-ene; TMS-protected cholest-4-ene-3β,6α-diol
EINECS	Contact for details

Quality Control

Our 3β,6α-Bis[(Trimethylsilyl)Oxy]Cholest-4-Ene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.