Description

[(5β-Cholestane-3α,6β-Diyl)Bisoxy]Bis(Trimethylsilane) is a high-purity, organosilicon-protected derivative of cholestane, a key steroid backbone. This compound is valued as a crucial advanced synthetic intermediate and a reference standard in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis and analysis of complex steroid-based molecules.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of novel steroid-based active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used for method development, calibration, and quality control in HPLC, GC-MS, and NMR analysis of steroid compounds.
• Biochemical Research: Employed in studies of sterol metabolism, membrane biophysics, and the development of biochemical probes.
• Process Chemistry: Serves as a building block in the development and scale-up of synthetic routes for complex organic molecules in fine chemical production.
• Material Science Research: Investigated as a precursor for functionalized organic materials and liquid crystals due to its rigid steroid core and silyl ether groups.

Basic Information

Product Name	[(5β-Cholestane-3α,6β-Diyl)Bisoxy]Bis(Trimethylsilane)
CAS No.	77828-34-3
Molecular Formula	C35H68O2Si2
Molecular Weight	577.07 g/mol
Synonyms	5β-Cholestane-3α,6β-diol bis(trimethylsilyl) ether; 3α,6β-Bis(trimethylsilyloxy)-5β-cholestane; Cholestane-3α,6β-diol, bis(trimethylsilyl) ether; 5β-Cholestane-3α,6β-diyl bis(trimethylsilyl) ether; 3α,6β-Di-O-trimethylsilyl-5β-cholestane; TMS ether of cholestane-3α,6β-diol; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [(5β-Cholestane-3α,6β-Diyl)Bisoxy]Bis(Trimethylsilane) is produced under a strict quality management system. Every batch undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere (argon or nitrogen), please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.