Description

3β,6α-Bis[(Trimethylsilyl)Oxy]-5α-Cholestane is a high-purity, silylated derivative of a cholestane steroid, primarily used as a critical intermediate in advanced organic synthesis. This compound is valued for its role in protecting hydroxyl groups and facilitating complex multi-step reactions, particularly in pharmaceutical research and development. It is essential for chemists and manufacturers in the life sciences sector who require reliable, high-quality building blocks for producing novel steroid-based compounds and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used in multi-step synthesis for the protection of hydroxyl groups via trimethylsilyl (TMS) ether formation, enabling complex molecular transformations.
• Biochemical Research: Serves as a standard or reference compound in metabolic pathway studies and steroid hormone research.
• Fine Chemical Production: Employed in the manufacture of specialized, high-value chemical products requiring precise steroid frameworks.
• Academic & Industrial R&D: Utilized in laboratories for method development and exploring new synthetic routes in medicinal chemistry.

Basic Information

Product Name	3β,6α-Bis[(Trimethylsilyl)Oxy]-5α-Cholestane
CAS No.	77828-32-1
Molecular Formula	C33H62O2Si2
Molecular Weight	546.99 g/mol
Synonyms	5α-Cholestane-3β,6α-diol bis(trimethylsilyl) ether; 3β,6α-Bis(trimethylsiloxy)-5α-cholestane; Cholestane-3β,6α-diol, bis(trimethylsilyl) ether; 5α-Cholestane-3β,6α-diyl bis(oxy)bis(trimethylsilane); 3β,6α-Di-O-trimethylsilyl-5α-cholestane
EINECS	Contact for details

Quality Control

Our 3β,6α-Bis[(Trimethylsilyl)Oxy]-5α-Cholestane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.