Description

6β-[(Trimethylsilyl)Oxy]-5β-Cholestan-3-One CAS NO 77828-30-9 is a high-purity, functionalized steroidal intermediate featuring a strategically protected hydroxyl group. This compound is critical for advanced organic synthesis, particularly in the development of novel steroid-based pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in steroid chemistry, hormone research, and the synthesis of complex natural products.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroid drugs and hormone analogs.
• Biochemical Research: Used as a precursor or standard in metabolic pathway studies and enzyme inhibition research related to cholesterol and steroid hormones.
• Organic Synthesis: Serves as a protected synthon for introducing the cholestane skeleton into more complex molecular architectures.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Material Science Research: Investigated for potential use in the development of advanced organic materials and liquid crystals.

Basic Information

Item	Details
Product Name	6β-[(Trimethylsilyl)Oxy]-5β-Cholestan-3-One
CAS No.	77828-30-9
Molecular Formula	C₃₀H₅₄O₂Si
Molecular Weight	474.84 g/mol
Synonyms	5β-Cholestan-3-one, 6β-[(trimethylsilyl)oxy]-; 6β-(Trimethylsiloxy)-5β-cholestan-3-one; 6β-Hydroxy-5β-cholestan-3-one trimethylsilyl ether; 6-TMS-oxy-5β-cholestan-3-one; Cholestan-3-one, 6β-[(trimethylsilyl)oxy]-5β-; 6β-Trimethylsilyloxy-5β-cholestan-3-one; 77828-30-9
EINECS	Contact for details

Quality Control

Our 6β-[(Trimethylsilyl)Oxy]-5β-Cholestan-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.