Description

Ethyl 5-(Chloromethyl)-2,6-Dimethylnicotinate is a high-purity, functionalized pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the construction of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those containing nicotinic acid or pyridine-based pharmacophores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive chloromethyl group.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functional organic materials, such as metal-organic frameworks (MOFs) or organic semiconductors, due to its modifiable structure.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	Ethyl 5-(Chloromethyl)-2,6-Dimethylnicotinate
CAS No.	77825-10-6
Molecular Formula	C11H14ClNO2
Molecular Weight	227.69 g/mol
Synonyms	5-(Chloromethyl)-2,6-dimethylnicotinic acid ethyl ester; Ethyl 5-(chloromethyl)-2,6-dimethylpyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 5-(chloromethyl)-2,6-dimethyl-, ethyl ester; 2,6-Dimethyl-5-chloromethylnicotinic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 5-(Chloromethyl)-2,6-Dimethylnicotinate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.