Description

Methyl 2-Fluoro-3,3,3-Trimethoxypropanoate is a specialized fluorinated organic ester building block of significant interest in advanced synthetic chemistry. Its unique structure, featuring a fluorine atom and three methoxy groups, makes it a valuable precursor for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought after by R&D chemists and process development scientists for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), leveraging the fluorine atom to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorinated moiety can enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and coatings with tailored surface properties.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex ether and ester linkages in multi-step synthetic routes.
• Fluorine Chemistry Research: A valuable substrate for studying novel fluorination reactions and the development of new synthetic methodologies.

Basic Information

Product Name	Methyl 2-Fluoro-3,3,3-Trimethoxypropanoate
CAS No.	77778-66-6
Molecular Formula	C7H13FO5
Molecular Weight	196.17 g/mol
Synonyms	Methyl 2-fluoro-3,3,3-trimethoxypropionate; 2-Fluoro-3,3,3-trimethoxypropionic acid methyl ester; Propanoic acid, 2-fluoro-3,3,3-trimethoxy-, methyl ester; Methyl α-fluoro-β,β,β-trimethoxypropionate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Fluoro-3,3,3-Trimethoxypropanoate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. Keep away from incompatible materials such as strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.