Description

Ethyl 2-Bromo-2-(4-Methoxyphenyl)Acetate is a high-value brominated aromatic ester building block, essential for advanced organic synthesis. Its structure, featuring both a reactive α-bromo ester moiety and a 4-methoxyphenyl group, makes it a versatile precursor for constructing complex molecules with high precision. This compound is particularly critical for research and development chemists in the pharmaceutical and agrochemical sectors, where it is used to introduce key molecular fragments in the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators, leveraging the methoxyphenyl group for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers for advanced polymers and liquid crystals.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Ethyl 2-Bromo-2-(4-Methoxyphenyl)Acetate
CAS No.	77629-83-5
Molecular Formula	C11H13BrO3
Molecular Weight	273.12 g/mol
Synonyms	Ethyl α-Bromo-4-methoxyphenylacetate; 2-Bromo-2-(4-methoxyphenyl)acetic acid ethyl ester; Ethyl (4-Methoxyphenyl)bromoacetate; 4-Methoxyphenylbromoacetic Acid Ethyl Ester; α-Bromo-4-methoxybenzeneacetic Acid Ethyl Ester; p-Methoxyphenylbromoacetic Acid Ethyl Ester; Bromo(4-methoxyphenyl)acetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Bromo-2-(4-Methoxyphenyl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.