Description

5-((2S)Pyrrolidin-2-Yl)-2-Methylpyridine is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its core value lies in its defined stereochemistry and fused heterocyclic structure, which are critical for imparting specific biological activity and physicochemical properties in target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of potential drug candidates, especially for neurological disorders.
• Ligand Synthesis: Used in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Serves as a building block for novel crop protection agents and pesticides.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme function and receptor interactions.
• Asymmetric Catalysis: Acts as a precursor for chiral catalysts used in stereoselective synthesis.
• Academic & Industrial R&D: Fundamental research compound in medicinal chemistry and synthetic methodology development.

Basic Information

Product Name	5-((2S)Pyrrolidin-2-Yl)-2-Methylpyridine
CAS No.	77629-50-6
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	(2S)-2-(6-Methylpyridin-3-yl)pyrrolidine; (S)-2-(6-Methyl-3-pyridinyl)pyrrolidine; 5-[(2S)-2-Pyrrolidinyl]-2-methylpyridine; 2-Methyl-5-((S)-pyrrolidin-2-yl)pyridine; (S)-2-(6-Methylpyridin-3-yl)pyrrolidine; 77629-50-6; L-2-(6-Methyl-3-pyridyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 5-((2S)Pyrrolidin-2-Yl)-2-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.