Description

Cholesterol Isobutyl Carbonate is a high-purity, chemically modified derivative of cholesterol, where the hydroxyl group is protected as an isobutyl carbonate ester. This modification enhances the compound's stability and solubility profile, making it a valuable intermediate for advanced synthesis. It is primarily utilized in the pharmaceutical and life sciences sectors for research and development, particularly in the synthesis of novel drug candidates, prodrugs, and specialized lipid conjugates. Its consistent quality is critical for ensuring reproducible results in sensitive applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroidal drugs and targeted therapeutic agents.
• Prodrug Development: Used to create more bioavailable or targeted prodrug forms of active pharmaceutical ingredients (APIs).
• Lipid Conjugate Synthesis: Serves as a precursor for creating cholesterol-based lipid conjugates used in drug delivery systems like liposomes.
• Biochemical Research: Employed in academic and industrial R&D for studying membrane biology, lipid metabolism, and signaling pathways.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development and quality control.
• Cosmetic Ingredient Synthesis: Intermediate for producing specialty esters used in high-end skincare formulations.

Basic Information

Product Name	Cholesterol Isobutyl Carbonate
CAS No.	77546-35-1
Molecular Formula	C32H54O3
Molecular Weight	486.78 g/mol
Synonyms	Cholest-5-en-3β-ol Isobutyl Carbonate; 3β-Hydroxycholest-5-ene Isobutyl Carbonate; Isobutyl Cholesteryl Carbonate; Cholesterol Carbonate Isobutyl Ester; 5-Cholesten-3β-ol, Isobutyl Carbonate; (3β)-Cholest-5-en-3-yl Isobutyl Carbonate
EINECS	Contact for details

Quality Control

Our Cholesterol Isobutyl Carbonate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals. We provide full traceability and a Certificate of Analysis (COA) with every shipment, ensuring compliance with relevant industry standards for research and pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.