Description

(1)Benzopyrano(2,3-B)(1,5)Benzodiazepin-13(6H)-One, 2-Chloro-6-(Phenyl Methyl)- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders and other therapeutic areas. It is primarily sought by R&D laboratories, contract manufacturing organizations (CMOs), and pharmaceutical companies engaged in the development of new chemical entities (NCEs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel benzodiazepine and benzopyranodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Essential for medicinal chemistry programs exploring new therapeutic agents for CNS disorders, anxiety, and sleep-related conditions.
• Preclinical Studies: Used in the preparation of candidate drug molecules for pharmacological screening and efficacy testing.
• Process Chemistry: Serves as a critical intermediate in scale-up and optimization studies for new drug manufacturing processes.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and structure-activity relationships (SAR).

Basic Information

Product Name	(1)Benzopyrano(2,3-B)(1,5)Benzodiazepin-13(6H)-One, 2-Chloro-6-(Phenyl Methyl)-
CAS No.	77436-72-7
Molecular Formula	C22H15ClN2O2
Molecular Weight	374.82 g/mol
Synonyms	2-Chloro-6-(phenylmethyl)-6H,13H-[1]benzopyrano[2,3-b][1,5]benzodiazepin-13-one; 2-Chloro-6-benzyl-6H,13H-[1]benzopyrano[2,3-b][1,5]benzodiazepin-13-one; 2-Chloro-6-benzyl-13H-[1]benzopyrano[2,3-b][1,5]benzodiazepin-13-one; 77436-72-7; Benzopyranobenzodiazepinone derivative
EINECS	Contact for details

Quality Control

Our production of (1)Benzopyrano(2,3-B)(1,5)Benzodiazepin-13(6H)-One, 2-Chloro-6-(Phenyl Methyl)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.