Description

8-Bromooctanoic Acid tert-Butyl Ester is a high-purity, protected carboxylic acid derivative that serves as a versatile building block in advanced organic synthesis. Its value lies in the combination of a reactive bromoalkyl chain and a base-labile tert-butyl ester protecting group, enabling precise, multi-step molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials industries who require reliable, high-quality intermediates for complex molecule development.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in the synthesis of compounds with long-chain alkyl functionalities.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and plant growth regulators that require specific alkyl chain modifications.
• Polymer & Material Science: Serves as a monomer or functionalization agent for creating specialty polymers with tailored properties like hydrophobicity or reactivity.
• Liquid Crystal & OLED Material Precursor: Employed in the synthesis of advanced organic electronic materials where controlled chain length and terminal functionality are critical.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Negishi, or Kumada couplings to form carbon-carbon bonds.
• Peptidomimetics & Bio-Conjugation: Useful for introducing lipophilic chains or linker arms into peptides and other biomolecules.
• Organic Synthesis Building Block: The tert-butyl ester can be selectively deprotected under mild acidic conditions, allowing for sequential synthetic strategies.

Basic Information

Product Name	8-Bromooctanoic Acid tert-Butyl Ester
CAS No.	77383-17-6
Molecular Formula	C₁₂H₂₃BrO₂
Molecular Weight	279.22 g/mol
Synonyms	tert-Butyl 8-bromooctanoate; 8-Bromo-octanoic acid tert-butyl ester; Octanoic acid, 8-bromo-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 8-bromooctanoate; 8-Bromooctanoic acid 1,1-dimethylethyl ester; Bromooctanoic acid tert-butyl ester; t-Butyl 8-bromooctanoate
EINECS	Contact for details

Quality Control

Every batch of 8-Bromooctanoic Acid tert-Butyl Ester is manufactured and tested under a strict quality management system. We ensure high chemical purity and lot-to-lot consistency through advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting cGMP and ISO standards for intermediate chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Related Substances (GC)	Total impurities ≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.