Description

3-Chloro-2-Iodopyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This high-purity compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen functionalities into heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the pyridine core provides bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in cross-coupling reactions like Suzuki-Miyaura and Buchwald-Hartwig amination.
• Material Science Research: Building block for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems due to its reactive halogen sites.
• Custom Synthesis and Contract Manufacturing: A high-demand intermediate for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Chloro-2-Iodopyridine
CAS No.	77332-89-9
Molecular Formula	C5H3ClIN
Molecular Weight	239.44 g/mol
Synonyms	2-Iodo-3-chloropyridine; 3-Chloro-2-iodopyridine; Pyridine, 3-chloro-2-iodo-; 3-Chloro-2-iodo-pyridine; 2-Iodo-3-chloro-pyridine; 3-Chloro-2-(iodo)pyridine
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.