Description

(3-Chloropyridin-4-Yl)(Phenyl)Methanol CAS NO 77332-81-1 is a versatile chiral building block and intermediate of significant importance in advanced organic synthesis. Its value lies in its functionalized pyridine and benzhydrol structure, which serves as a key precursor for the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its halogenated pyridine moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its aromatic systems.
• Custom Synthesis and Contract Manufacturing: A key building block for custom synthesis projects and scale-up services for specialized chemical entities.

Basic Information

Product Name	(3-Chloropyridin-4-Yl)(Phenyl)Methanol
CAS No.	77332-81-1
Molecular Formula	C12H10ClNO
Molecular Weight	219.67 g/mol
Synonyms	4-Chloro-α-phenyl-3-pyridinemethanol; (3-Chloro-4-pyridinyl)phenylmethanol; α-Phenyl-3-chloro-4-pyridinemethanol; Benzhydrol, 3-chloro-4-pyridinyl-; 3-Chloro-4-pyridylphenylmethanol; (Phenyl)(3-chloro-4-pyridinyl)methanol; 3-Chloro-4-pyridinylphenylmethanol
EINECS	Contact for details

Quality Control

Our (3-Chloropyridin-4-Yl)(Phenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.