Description

Peg4-Coome CAS NO 77303-63-0 is a high-purity polyethylene glycol (PEG) derivative, specifically a tetraethylene glycol monoester, valued for its role as a versatile linker and solubilizing agent. Its bifunctional nature, featuring a reactive ester group and a hydrophilic PEG chain, makes it essential for modifying biomolecules and fine-tuning material properties. This compound is particularly critical for researchers and manufacturers in the pharmaceutical, bioconjugation, and advanced materials sectors who require reliable, high-quality building blocks for their synthesis workflows.

Application

• Pharmaceutical Intermediates: Serves as a key linker in the synthesis of prodrugs, antibody-drug conjugates (ADCs), and targeted therapeutic agents.
• Bioconjugation Chemistry: Used to PEGylate peptides, proteins, and oligonucleotides to enhance solubility, stability, and circulation time.
• Polymer & Material Science: Acts as a functional monomer or cross-linking agent in the development of hydrogels, smart polymers, and biocompatible coatings.
• Surface Modification: Employed to create hydrophilic, protein-resistant surfaces on medical devices and diagnostic platforms.
• Cosmetic & Personal Care Formulations: Functions as a mild surfactant and conditioning agent in high-performance skincare products.
• Research & Development: A valuable tool compound in academic and industrial R&D for exploring new drug delivery systems and material interfaces.

Basic Information

Product Name	Peg4-Coome
CAS No.	77303-63-0
Molecular Formula	C13H24O8
Molecular Weight	308.33 g/mol
Synonyms	2,5,8,11-Tetraoxatridecan-13-oic acid, methyl ester; Tetraethylene glycol monomethyl ether monoacetate; Methyl tetraethylene glycol acetate; PEG4 methyl ester; mPEG4-CH2COOMe; 3,6,9,12-Tetraoxapentadecanoic acid, methyl ester; HO-PEG4-CH2COOMe; Tetraethylene glycol mono(methyl acetate)
EINECS	Contact for details

Quality Control

Every batch of Peg4-Coome is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency that meets the demanding requirements of pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.