Description

(R)-(+)-Methyl (R)-2-Chloropropionate CAS NO 77287-29-7 is a high-purity chiral building block and a key intermediate in asymmetric synthesis. Its defined stereochemistry is critical for producing enantiomerically pure compounds, which are essential in advanced pharmaceutical and agrochemical research. This product is primarily needed by R&D chemists and process development scientists in the pharmaceutical, fine chemical, and specialty materials industries.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of enantiomerically pure drugs.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry is required for biological activity and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric catalysis.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(R)-(+)-Methyl (R)-2-Chloropropionate
CAS No.	77287-29-7
Molecular Formula	C4H7ClO2
Molecular Weight	122.55 g/mol
Synonyms	(R)-(+)-Methyl 2-chloropropanoate; (R)-Methyl 2-chloropropionate; Methyl (R)-2-chloropropanoate; (R)-2-Chloropropionic acid methyl ester; (R)-Methyl α-chloropropionate; (+)-Methyl 2-chloropropionate; (R)-Methyl chloropropionate; (R)-2-Chloro-1-methoxy-1-oxopropane
EINECS	Contact for details

Quality Control

Our (R)-(+)-Methyl (R)-2-Chloropropionate is manufactured under strict quality control protocols to ensure high chemical and enantiomeric purity. Each batch is analyzed using advanced chromatographic (HPLC, GC) and spectroscopic (NMR) techniques. Certificates of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Clear colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Specific Rotation [α]D20	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.