Description

Propanoic Acid, 2-(Phenylmethoxy)-, Methyl Ester, (2S)- is a chiral, non-racemic organic compound belonging to the class of α-alkoxy esters. This specific stereochemistry makes it a valuable chiral building block and intermediate in advanced organic synthesis. It is primarily sought after by research and development chemists and process development teams in the pharmaceutical and fine chemical industries. The compound's structure is designed for the controlled introduction of stereocenters in complex molecule assembly.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in routes requiring specific stereochemical control.
• Asymmetric Synthesis: Used as a starting material or reagent in stereoselective reactions, including alkylations, aldol additions, and reductions.
• Natural Product Synthesis: Serves as a building block in the total synthesis of complex natural products where the (S)-configured alkoxy ester moiety is required.
• Ligand and Catalyst Preparation: Can be utilized in the preparation of chiral ligands or organocatalysts for enantioselective transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that demand high enantiomeric purity.
• Academic and Industrial Research: A critical material for methodological development in synthetic organic chemistry and process chemistry optimization.

Basic Information

Product Name	Propanoic Acid, 2-(Phenylmethoxy)-, Methyl Ester, (2S)-
CAS No.	77287-11-7
Molecular Formula	C11H14O3
Molecular Weight	194.23 g/mol
Synonyms	(S)-Methyl 2-(Benzyloxy)propanoate; (S)-2-Benzyloxypropionic Acid Methyl Ester; Methyl (S)-2-(Benzyloxy)propionate; (S)-α-(Benzyloxy)propionic Acid Methyl Ester; L-Methyl 2-(Benzyloxy)propanoate; (2S)-2-(Phenylmethoxy)propanoic Acid Methyl Ester; Methyl (2S)-2-(Benzyloxy)propanoate
EINECS	Contact for details

Quality Control

Our production of Propanoic Acid, 2-(Phenylmethoxy)-, Methyl Ester, (2S)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, to confirm identity, chemical purity, and enantiomeric excess (ee). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.