Description

(1R,2S,6β)-3α,7,7-Trimethylspiro[Bicyclo[4.1.0]Heptane-2,1'-[2]Cyclopentene]-3'-Carbaldehyde is a high-purity, specialized spirocyclic aldehyde building block of significant interest in advanced organic synthesis. Its unique and complex molecular architecture makes it a critical intermediate for constructing novel compounds with specific three-dimensional frameworks. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fragrance industries who require precise, high-quality chiral synthons.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for complex, sterically constrained molecules.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides where its spirocyclic structure can contribute to unique biological activity and stability.
• Fragrance & Flavor Chemistry: Acts as a building block for creating novel synthetic aroma chemicals with complex, woody, or amber-like olfactory profiles.
• Material Science: Investigated as a monomer or cross-linking agent for producing specialty polymers with tailored thermal or mechanical properties.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral template in the development of new asymmetric catalytic systems.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic synthesis, including cycloaddition reactions and stereoselective transformations.

Basic Information

Item	Details
Product Name	(1R,2S,6β)-3α,7,7-Trimethylspiro[Bicyclo[4.1.0]Heptane-2,1'-[2]Cyclopentene]-3'-Carbaldehyde
CAS No.	77283-84-2
Molecular Formula	C15H20O
Molecular Weight	216.32 g/mol
Synonyms	(1R,2S,6S)-3,7,7-Trimethylspiro[bicyclo[4.1.0]heptane-2,1'-cyclopent-2-ene]-3'-carboxaldehyde; (-)-α-Santalal; (1R,2S,6S)-3,7,7-Trimethylspiro[bicyclo[4.1.0]hept-3-ene-2,1'-cyclopentan]-3'-carbaldehyde; Santalal; Spirocyclic aldehyde CAS 77283-84-2
EINECS	Contact for details

Quality Control

Every batch of our (1R,2S,6β)-3α,7,7-Trimethylspiro[Bicyclo[4.1.0]Heptane-2,1'-[2]Cyclopentene]-3'-Carbaldehyde undergoes rigorous analytical testing to ensure high chemical purity, correct stereochemistry, and batch-to-batch consistency. Our quality protocols are designed to meet the stringent requirements of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC/GC), chiral purity, identity (IR, NMR), and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.