Description

Methyl 1,4-Dioxaspiro[4.4]Nonane-7-Carboxylate is a high-value, protected ester derivative of a spirocyclic ketone, serving as a crucial chiral building block in advanced organic synthesis. Its unique spiroacetal structure provides exceptional stereochemical control, making it indispensable for constructing complex molecular architectures with high precision. This intermediate is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced, stereochemically-defined pesticides and herbicides.
• Fine Chemical Production: Serves as a versatile precursor for fragrances, flavors, and other high-value specialty chemicals requiring specific stereochemistry.
• Academic & Industrial Research: A valuable reagent in methodological development for asymmetric synthesis and catalysis studies.
• Material Science: Potential application as a monomer or precursor for polymers with unique thermal or optical properties.

Basic Information

Product Name	Methyl 1,4-Dioxaspiro[4.4]Nonane-7-Carboxylate
CAS No.	77250-34-1
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	Methyl 1,4-Dioxaspiro[4.4]nonane-7-carboxylate; 7-Methoxycarbonyl-1,4-dioxaspiro[4.4]nonane; Methyl 7-oxo-1,4-dioxaspiro[4.4]nonane-7-carboxylate; 1,4-Dioxaspiro[4.4]nonane-7-carboxylic acid, methyl ester; Spiroacetal Ester; Protected Cyclohexanone Ester; Chiral Spiroketal Ester
EINECS	Contact for details

Quality Control

Our Methyl 1,4-Dioxaspiro[4.4]Nonane-7-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis (HPLC/GC), to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.