Description

Cyclohexanone o-(Trimethylsilylmethyl)Oxime CAS NO 77214-54-1 is a specialized organosilicon compound featuring a reactive oxime functional group. This chemical is a valuable synthetic intermediate, prized for its role in introducing the trimethylsilylmethyl (TMSM) moiety into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and advanced materials sectors. Its unique structure enables key transformations in the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing functionalized side chains.
• Organic Synthesis Reagent: Used in nucleophilic addition and cyclization reactions to construct complex heterocyclic and carbocyclic frameworks.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the research and development of silicon-containing polymers and advanced organic-inorganic hybrid materials.
• Cross-Coupling Reactions: Acts as a substrate or reagent in palladium-catalyzed and other metal-mediated coupling processes.
• Protecting Group Chemistry: The oxime and silyl groups can be utilized for the temporary protection of ketone functionalities during multi-step syntheses.

Basic Information

Product Name	Cyclohexanone o-(Trimethylsilylmethyl)Oxime
CAS No.	77214-54-1
Molecular Formula	C10H21NOSi
Molecular Weight	199.37 g/mol
Synonyms	Cyclohexanone, O-[(trimethylsilyl)methyl]oxime; O-[(Trimethylsilyl)methyl]cyclohexanone oxime; Cyclohexanone O-(trimethylsilylmethyl)oxime; (Trimethylsilylmethyl)oxyimino-cyclohexane; TMSM-Cyclohexanone oxime
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, assay, and impurity profiles are available upon request. We adhere to strict in-process controls to guarantee the reliability required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.