Description

5-Bromo-2-Pyridinecarboxylic Acid Ethyl Ester is a versatile brominated pyridine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a reactive handle for cross-coupling reactions and further functionalization, enabling the efficient construction of complex molecular architectures. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where precision and reliability are paramount.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional organic materials, including liquid crystals and organic semiconductors.
• Cross-Coupling Reactions: A valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying biological systems and enzyme activity.

Basic Information

Product Name	5-Bromo-2-Pyridinecarboxylic Acid Ethyl Ester
CAS No.	77199-09-8
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	Ethyl 5-Bromopicolinate; 5-Bromo-2-pyridinecarboxylic acid ethyl ester; 5-Bromopicolinic Acid Ethyl Ester; Ethyl 5-Bromo-2-pyridinecarboxylate; 2-Pyridinecarboxylic acid, 5-bromo-, ethyl ester; 5-Bromo-pyridine-2-carboxylic acid ethyl ester; 5-Bromopicolinate ethyl ester
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Pyridinecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.