Description

Vitamin K1 Aglycone Iii is a specific, high-purity form of the essential fat-soluble vitamin K1, distinguished by its aglycone structure. This compound is critical for its role as a key biochemical precursor and intermediate in the synthesis of more complex vitamin K derivatives and active pharmaceutical ingredients. It is primarily required by manufacturers in the pharmaceutical, nutraceutical, and advanced research sectors for applications demanding precise chemical structure and high biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial starting material or intermediate in the synthesis of specialized vitamin K-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and reagent in metabolic studies, enzyme research, and investigations into blood coagulation pathways.
• Nutraceutical Formulation: Incorporated into advanced dietary supplements and specialized nutritional products where the specific aglycone form is required for enhanced bioavailability or targeted action.
• Cosmeceutical Applications: Employed in the development of high-end skincare products for its potential role in supporting skin health and addressing concerns related to vascular integrity.
• Veterinary Medicine: Used in the formulation of specialized treatments and supplements for animals, particularly for conditions related to blood clotting and bone metabolism.

Basic Information

Product Name	Vitamin K1 Aglycone Iii
CAS No.	77179-33-0
Molecular Formula	C31H46O2
Molecular Weight	450.70 g/mol
Synonyms	Phylloquinone Aglycone; Vitamin K1(20); 2-Methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]naphthalene-1,4-dione; 2-Methyl-3-phytyl-1,4-naphthoquinone Aglycone; 1,4-Naphthoquinone, 2-methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-, (R-(R*,R*-(E)))-; Menadione K1 Aglycone; Phytomenadione Aglycone; K1 Aglycone Form III
EINECS	Contact for details

Quality Control

Our Vitamin K1 Aglycone Iii is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical testing including HPLC, GC, and spectroscopic methods. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We adhere to cGMP principles where applicable to support its use in regulated pharmaceutical and nutraceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature of 15-25°C (59-77°F) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.