Description

(2R, 4'S, 8'S)-α-Tocopherol CAS NO 77171-98-3 is a specific, high-purity stereoisomer of natural vitamin E, distinguished by its precise (2R, 4'S, 8'S) configuration. This compound matters for its superior biological activity and stability compared to synthetic mixtures, making it the preferred choice for high-performance applications where efficacy and quality are paramount. It is critically needed by manufacturers in the pharmaceutical, nutraceutical, and premium cosmetic industries for formulating advanced dietary supplements, injectable medications, and anti-aging skincare products.

Application

• Pharmaceutical Formulations: Active pharmaceutical ingredient (API) in prescription and over-the-counter vitamin E supplements, including softgel capsules and injectable solutions.
• Nutraceutical & Dietary Supplements: Key ingredient in high-potency vitamin E supplements, multivitamin complexes, and specialized health products targeting antioxidant support.
• Cosmetics & Personal Care: Potent antioxidant and skin-conditioning agent in premium anti-aging serums, creams, lotions, and sun care products.
• Functional Foods & Beverages: Fortification agent for foods and drinks requiring a stable, bioavailable form of vitamin E.
• Animal Nutrition (Premix): Essential vitamin component in high-grade feed premixes for livestock, poultry, and pets.
• Biochemical Research: Reference standard and reagent in life science research, clinical diagnostics, and analytical laboratories.

Basic Information

Item	Details
Product Name	(2R, 4'S, 8'S)-α-Tocopherol
CAS No.	77171-98-3
Molecular Formula	C29H50O2
Molecular Weight	430.71 g/mol
Synonyms	d-α-Tocopherol; RRR-α-Tocopherol; Natural Vitamin E; (R,R,R)-α-Tocopherol; 2R,4'R,8'R-α-Tocopherol; 5,7,8-Trimethyltocol; Vitamin E (natural form); EINECS 278-769-9
EINECS	278-769-9

Quality Control

Our (2R, 4'S, 8'S)-α-Tocopherol is manufactured under strict quality systems. It is typically tested to meet or exceed relevant standards for high-purity applications, including those guided by USP-NF and Ph. Eur. monographs. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure supply reliability and regulatory compliance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) in a cool, dry place at temperatures between 2°C and 8°C (refrigerated) for long-term stability. This product is easily oxidized and light-sensitive; prolonged exposure to air, heat, or light should be avoided to maintain potency and shelf life.

Specification

Item	Specification
Appearance	Clear, pale yellow to brownish viscous oil
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 96.0%
Specific Rotation [α]20/D	+0.20° to +0.30°
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.