Description

4-Azidobenzoylglycyllysine is a specialized synthetic peptide derivative, primarily utilized as a key intermediate in advanced biochemical research and development. Its core value lies in its unique azido functional group, which enables highly specific bio-conjugation and labeling applications through click chemistry. This compound is essential for researchers and manufacturers in the fields of pharmaceutical development, proteomics, and the creation of novel diagnostic tools and targeted therapeutics.

Application

• Bioconjugation Reagent: A critical building block for site-specific protein and antibody labeling via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
• Proteomics Research: Used in activity-based protein profiling (ABPP) and the development of chemical probes to study enzyme function and protein interactions.
• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of peptide-drug conjugates (PDCs) and other targeted biotherapeutics.
• Diagnostic Development: Employed in the design and fabrication of advanced immunoassays and biosensors for enhanced detection sensitivity.
• Materials Science: Facilitates the surface functionalization of nanoparticles and polymers for biomedical and biotechnological applications.
• Chemical Biology Tool: Enables the study of post-translational modifications and cellular pathways through incorporation into designed peptide sequences.

Basic Information

Product Name	4-Azidobenzoylglycyllysine
CAS No.	77162-73-3
Molecular Formula	C15H20N6O4
Molecular Weight	348.36 g/mol
Synonyms	Nα-(4-Azidobenzoyl)-Gly-Lys; 4-Azidobenzoyl-Gly-Lys-OH; Glycyllysine, N-(4-azidobenzoyl)-; N-(4-Azidobenzoyl)glycyl-L-lysine; ABG-Lys; Azido-PEG2-Lys; Click Chemistry Peptide Intermediate; L-Lysine, N2-(4-azidobenzoyl)-N6-glycyl-
EINECS	Contact for details

Quality Control

Our 4-Azidobenzoylglycyllysine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool, and well-ventilated place. Due to its hygroscopic and light-sensitive nature, the product should be handled under inert atmosphere when appropriate and allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.