Description

4-Bromo-2-Chloro-6-Methylphenyl Isocyanate is a versatile and highly reactive aromatic isocyanate building block, essential for the synthesis of advanced chemical intermediates. Its core value lies in its ability to introduce the isocyanate functional group into complex molecular architectures, enabling the creation of novel compounds with tailored properties. This product is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where its halogenated phenyl structure contributes to biological activity.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polyurethanes, polyureas, and other polymers requiring specific thermal or chemical resistance.
• Chemical Research: A crucial reagent in organic synthesis for constructing urea and carbamate derivatives via reactions with amines and alcohols.
• Material Science: Employed in the surface modification of materials and the creation of advanced coatings and adhesives with enhanced performance characteristics.

Basic Information

Product Name	4-Bromo-2-Chloro-6-Methylphenyl Isocyanate
CAS No.	77159-77-4
Molecular Formula	C8H5BrClNO
Molecular Weight	246.49 g/mol
Synonyms	2-Chloro-6-methyl-4-bromophenyl isocyanate; 1-Bromo-3-chloro-5-isocyanato-2-methylbenzene; 4-Bromo-2-chloro-6-methylbenzenisocyanate; Isocyanic acid, 4-bromo-2-chloro-6-methylphenyl ester; (4-Bromo-2-chloro-6-methylphenyl)isocyanate
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-6-Methylphenyl Isocyanate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for each lot and provided upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.