Description

n-[1-(3-Chloropyridin-2-Yl)Piperidin-4-Yl]Acetamide is a high-purity, advanced pharmaceutical intermediate with a distinct molecular structure combining pyridine and piperidine moieties. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its specific scaffold enables targeted pharmacological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• API Manufacturing: Employed in controlled, multi-step synthetic routes for the production of high-value active pharmaceutical ingredients under GMP conditions.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	n-[1-(3-Chloropyridin-2-Yl)Piperidin-4-Yl]Acetamide
CAS No.	77145-34-7
Molecular Formula	C12H16ClN3O
Molecular Weight	253.73 g/mol
Synonyms	N-[1-(3-Chloro-2-pyridinyl)-4-piperidinyl]acetamide; 1-(3-Chloropyridin-2-yl)piperidin-4-amine, N-acetyl derivative; Acetamide, N-[1-(3-chloro-2-pyridinyl)-4-piperidinyl]-; 77145-34-7; 2-Chloro-3-(4-acetamidopiperidin-1-yl)pyridine; 3-Chloro-2-(4-acetamidopiperidin-1-yl)pyridine
EINECS	Contact for details

Quality Control

Our n-[1-(3-Chloropyridin-2-Yl)Piperidin-4-Yl]Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and compliance assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.